This technology involves using biodegradable polymeric nanoparticles loaded with the target drug as a new carrier to transport it across the intestinal epithelial tissues ensuring its bioavailability, stability and antigenicity in the body.
The biggest challenge of oral delivery route is that these protein-based drugs will be adversely exposed to acids and enzymes in the stomach loosening the intended effect in the course. At present, insulin is administered only by injection.
